PGA , PDO

PGA, PDO absorbable suture, 75cm with needle

PGA elicits minimal acute inflammatory reaction in tissues, which

is followed by gradual encapsulation of the suture by fibrous connective tissue. Progressive loss of tensile strength and eventual

absorption of PGA synthetic absorbable suture occurs by means

of hydrolysis, where the polymer degrades to either glycolic acid

or glycolic and lactic acids which are subsequently absorbed an-

metabolized by the body.

Absorption begins as a loss of tensile strength without appreciable

loss of mass. Implantation studies in animals indicate that PGAretains approximately 73% of its original tensile strength at two

weeks post implantation, with approximately 33% remaining at

three weeks. Absorption of PGA synthetic absorbable surgical

suture is essentially complete between 60 and 90 days.

PGA , PDO